Study Finds E-cigarette Users May Have More Lung Inflammation Than Smokers

Study Finds E-cigarette Users May Have More Lung Inflammation Than Smokers

E-Cigarette Use May Be More Harmful to Lungs Than Tobacco Smoking

According to a recent study published in The Journal of Nuclear Medicine, e-cigarette smokers exhibit more lung inflammation than those who smoke tobacco. The study is the first to use PET imaging to compare vapers’ lungs versus smokers.

E-cigarettes have become a significant industry, with a global market value of US$24.6 billion in 2022, a drastic increase from US$1.7 billion in 2013. This surge in sales is due to increased usage beyond ex-smokers, with one in ten middle to high-school students in the US currently using e-cigarettes.

Effects of E-cigarettes on Lungs

A recent pilot study at the University of Pennsylvania found that e-cigarette users show more lung inflammation than those who smoke tobacco or non-smokers. The study, which is the first of its kind, used PET imaging to examine lungs and assess the impact of vaping. The researchers found that e-cigarette smokers had significantly higher levels of an enzyme called inducible nitric oxide synthase (iNOS) in their lungs compared to non-smokers and those who smoke regular cigarettes.

The findings suggest that e-cigarette use may cause lung inflammation, which is even higher than for tobacco cigarette smokers. While this study has limitations due to its small sample size, it highlights the potential long-term harm of e-cigarette smoking and raises concerns about the overall safety and effectiveness of e-cigarettes.

Considerations for E-Cigarette Use

The utility of e-cigarettes is a complex issue as the cost-benefit analysis must be considered. While e-cigarettes may be useful as a smoking cessation tool or as a safer alternative to traditional cigarettes, users need to consider the potential risks and long-term health effects associated with vaping.

Helping people quit smoking tobacco is one such reason, as the rates of smoking-related diseases like Chronic Obstructive Pulmonary Disease (COPD) and cancer are lower in e-cigarette users compared to tobacco smokers. Thus, using e-cigarettes to quit smoking is a good first step, but it should not be the last step for smokers as the long-term effects of e-cigarettes are unknown. Therefore, it is important to weigh the potential risks and benefits of e-cigarette use and consider the long-term harm it may cause.


E-cigarettes can be a good smoking cessation tool for some individuals, but they are not without potential risks. Studies have shown that e-cigarettes can be effective in helping some smokers quit or reduce their tobacco use. Additionally, e-cigarettes may have lower rates of diseases like COPD and cancer compared to tobacco cigarettes. However, it is important to consult with a healthcare professional and carefully consider the potential advantages and disadvantages of using e-cigarettes as a means to quit smoking.

Vaping Daily Team

The Vaping Daily team is a collective of expert vapers. We tried hundreds of vapes and happily review them here. Our guides, reviews, and top lists share the best practices from our experience. Subscribe to e-mails to get vape news and deals.

### Additional Information:
– [National Institute on Drug Abuse: Electronic Cigarettes](
– [American Lung Association: E-Cigarettes and Lung Health](
– [Centers for Disease Control and Prevention: Smoking and Tobacco Use](



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